Top 10 Health Benefits Of Lycopene, Side Effects, & Dosage

The many benefits of lycopene are reasons enough to look for food containing it. Foods that contain this pigment are often bright red, such as tomatoes, watermelons, and grapefruit.

The health benefits of lycopene have been well documented. They can help treat a wide range of cancers (1). They may also promote a healthy heart and vision.

This article discusses the benefits of lycopene, its sources, recommended dosage, and any potential side effects. Keep reading.

Know Your Ingredient: Lycopene

What Is It?
An organic, red-colored pigment found in tomatoes, watermelons, and grapefruits.

What Are Its Benefits?
It may aid in cancer treatment, promote heart, brain, and skin health, improve vision, strengthen bones, heal sunburns, and relieve pain.

Who Can Consume It?
It is naturally present in fruits and is safe for all.

How Often?
Lycopene supplements can be taken daily for 6 months in doses prescribed by your doctor.

Caution
Excess intake might cause skin discoloration. Also, the intake should be moderate during pregnancy or breastfeeding.

What Are The Health Benefits Of Lycopene?

The powerful antioxidant properties of lycopene fight free radicals and oxidative stress. They combat inflammation, thereby preventing serious ailments like cancer and heart disease. Lycopene also protects your skin, thanks to its photoprotective properties. Now, let’s take a closer look at how lycopene benefits your overall health.

1. May Aid Cancer Treatment

Lycopene fights inflammation, thereby showing promise in cancer prevention (2). It scavenges free radicals and reduces oxidative stress. This way, it prevents the potential transformation of normal cells to cancer cells. Studies suggest that this antioxidant is best absorbed when taken through foods that are heated than those that are raw.

Lycopene also has a role to play in the prevention of prostate cancer. It induces the release of certain detoxification proteins that help prevent prostate cancer (3). However, more studies and clinical trials are needed to establish this fact.

Tomatoes are among the richest sources of lycopene. Consuming cooked tomatoes, as discussed, ensures better lycopene absorption. Cooking breaks the cell walls of the vegetable and releases the antioxidant (4).

Tomatoes cooked in olive oil seem to have a much better bioavailability of lycopene (4).

Additionally, lycopene may also reduce the side effects of chemotherapy, thanks to its anti-inflammatory properties (5).

2. May Promote Heart Health

Lycopene is among the many carotenoid antioxidants in fruits and vegetables that promote heart health

(6).

The antioxidant effects of lycopene may promote heart health and prevent incidences of cardiovascular diseases (7). Though more human studies are required to validate this point, lycopene seems to show promise in promoting heart health.

Lycopene had also shown to benefit patients dealing with hypertension and atherosclerosisⁱ  A cardiovascular disease that occurs when there is a buildup of cholesterol plaque in artery walls obstructing normal blood flow. (8). However, the results of several studies have been slightly inconsistent.

3. May Improve Brain Health

Lycopene may play a role in the prevention and treatment of Alzheimer’s. Individuals with Alzheimer’s were found to have lower levels of serum lycopene. The antioxidant was found to attenuate oxidative damage (9).

Studies have found that this antioxidant can delay paralysis by correcting corrupted cells and protecting the healthy ones (9).

Lycopene can aid in stroke prevention. It fights free radicals that may damage the DNA and other fragile cell structures. It may protect cells in ways other antioxidants cannot.

In studies, men with the highest amount of lycopene in their blood were found to have 55% lower chances of having any kind of stroke (10).

Lycopene may achieve this by preventing blood from clotting (10).

Lycopene may also protect the nerves from the ill effects of high cholesterol (11).

Trivia

Although lycopene is a carotenoid, the body cannot convert it to vitamin A as it is an unsaturated straight-chain hydrocarbon and lacks terminal beta iodine rings.

4. May Enhance Vision

Lycopene may help reduce oxidative stress related to cataracts. In animal studies, rats fed with lycopene showed a visible improvement in cataracts (12).

Lycopene might be highly beneficial for eye health. The antioxidant may also cut the risk of age-related macular degenerationⁱ  An eye disease that blurs vision due to damage to the central part of the retina (macula), especially affecting people over the age of 55. . Patients dealing with the eye disease were found to have low serum levels of lycopene (13).

The major cause of almost all vision disorders is oxidative stress. Since lycopene battles oxidative stress, it may help prevent long-term vision issues (14).

5. May Strengthen Bones

In female rats, lycopene was found to promote bone mineral density. The antioxidant could fight oxidative stress and exert beneficial effects on bone health. Lycopene intake may facilitate bone formation and inhibit bone resorption (15).

Combining lycopene and exercise can also contribute to bone health (16).

In rat studies, treatment with lycopene had also restored bone strength and bone microarchitecture. It achieves this by fighting oxidative stress that might weaken bones (17).

6. Helps Heal Sunburn

Studies show that lycopene can offer protection against erythema (superficial reddening of the skin) induced by ultraviolet rays (18). Lycopene is an antioxidant efficient in scavenging free radicals.

The antioxidant is involved in the light-protecting system in plants and helps prevent UV damage in humans. Dietary carotenoids, like lycopene, may contribute to life-long protection against UV radiation (19). This way, the antioxidant can help heal sunburn.

Quick Tip

Applying tomatoes is the easiest way to use lycopene for healing sunburn. Use tomato slices soaked in buttermilk to soothe discomfort caused by sunburn.

7. Can Relieve Pain

Lycopene was found to reduce neuropathic pain in the case of peripheral nerve injury. It achieved this by reversing the functioning of tumor necrosis factor, which is a substance in the human body that triggers inflammation (20).

Lycopene also attenuated thermal hyperalgesia in rat models. Thermal hyperalgesia is the perception of heat as pain, especially at abnormally high sensitivity (21).

Lycopene also helps reduce the sensitization of pain receptors, thereby reducing pain (22).

8. May Treat Infertility

Lycopene was found to boost sperm count by as much as 70%. The antioxidant properties of lycopene may help boost sperm quality. Since the compound also cuts the risk of cancer of the prostate, it can further promote reproductive health (as the prostate gland makes seminal fluid) (23).

However, most studies done in this regard are observational (24). We need more concrete research to conclude.

Lycopene may also treat priapism in males. Priapism is a condition characterized by persistently painful erections of the penis. It can lead to the drying of the erectile tissue, eventually leading to erectile dysfunction (25).

9. Can Promote Skin Health

Lycopene is among the class of antioxidants that are known for their photoprotective properties. It (along with beta-carotene) is the dominating carotenoid in the human tissue and helps modulate skin properties (26).

This compound also mitigates oxidative damage in skin tissues (26).

Supplementing with lycopene was also found to improve skin texture and reduce the appearance of wrinkles (27).

10. May Protect Against Asthma

Lycopene is a dietary antioxidant that can help reduce allergic inflammation. A study conducted on mice found that lycopene reduced certain types of immune cells in the lungs and bloodstream and decreased the number of cells producing mucus in the airways. It may also decrease the allergic inflammation in the lungs and the body by regulating certain immune responses, showing a potential protective effect against asthma (28). Another study compared 40 individuals with asthma with 56 healthy people and found that the former had lower levels of serum lycopene and vitamin A compared to the healthy group (29). Therefore, consuming foods rich in lycopene and vitamin A could be beneficial for people with asthma.

As we saw, lycopene is among the most potent antioxidants. It scavenges free radicals and protects the body from the harmful effects of oxidative stress. Including foods rich in lycopene in your diet can go a long way in keeping you healthy and disease-free.

Lycopene is a carotenoid. It belongs to the class of antioxidants that are responsible for certain foods’ characteristic colors. Following are the foods rich in lycopene:

• Tomatoes – 1 cup of sun-dried tomatoes (54 grams) contains 25 milligrams of lycopene (30).
• Watermelon – 1 ½ cups of watermelon contain about 13 milligrams of lycopene (31).
• Bell peppers – 100 grams of bell peppers contain about 5 milligrams of lycopene (32).
• Papaya – 1 small fruit (157 grams) contains 2 milligrams of lycopene (33).
• Grapefruit – 1 cup of grapefruit (250 grams) contains about 1 milligram of lycopene (34).

According to a survey in 2017 tomatoes were the 2nd most consumed vegetables after potatoes in the United States. The consumption amounts to about 20.3 pounds every year. In 2020, about 12,619.2 tons of fresh tomatoes were harvested and 11,312,256 tons of processed tomatoes were harvested. Being rich in antioxidants, vitamin A and C it is added to various dishes in the US.

Including these foods in your diet on a regular basis can benefit your health in various ways. But what if you are short of time and cannot eat all these foods? Would supplements work?

What About Lycopene Supplements?

You may take lycopene through supplements. But research is inconclusive. Some reports suggest that the benefits of lycopene could be stronger when you get it from whole foods (35).

In other studies, smokers had a higher risk of cancer when on beta-carotene supplements (36).

Hence, talk to your nutritionist/health care provider before taking supplements. Remember, they are not replacements.

But even when you are taking lycopene through foods, you may want to keep a few things in mind.

Does Lycopene Have Any Side Effects?

• Lycopenemia

Lycopenemiaⁱ  A harmless skin condition causing discoloration due to excessive consumption of foods containing lycopene (responsible for red pigmentation). is a harmless skin condition caused by an excessive intake of foods containing lycopene. The symptoms include reddish discoloration of the skin (37).

• Pregnancy

The effects of lycopene during pregnancy are mixed. While a few reports state increased birth weight in infants, others show reduced infant birth weight post the intake of lycopene by the mothers (38). Hence, please consult your doctor before taking lycopene during pregnancy or breastfeeding.

Any Specific Dosage?

Experts recommend at least 10 milligrams of lycopene per day (10). The average lycopene intake in the United States is 5.7 mg to 10.5 mg per day, for every individual (39).

Infographic: Lycopene Supplement Forms

Lycopene is a pigment with many antioxidant properties and health benefits. It is found in many food sources and in different supplements. Check out the infographic below to learn more about the various lycopene supplement forms.

Illustration: StyleCraze Design Team

Frequently Asked Questions

Does lycopene help in weight loss?

Lycopene’s ability to induce weight loss is not proven, and also is highly unlikely. It is a powerful antioxidant that fights inflammation and oxidative stress, preventing related diseases.

Does lycopene increase testosterone levels?

Yes. Animal studies found that lycopene could significantly increase testosterone levels (40).

Is lycopene good for hair?

Yes. Lycopene may help promote hair growth and can be used as a part of hair loss treatments (41).

Is lycopene good for kidneys?

Lycopene supplementation effectively treats kidney issues and tissue inflammation (42).

Illustration: Does Ginger Aid Hair Growth? Benefits Uses And More

Image: Dall·E/StyleCraze Design Team

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Dr.Varsha PrabalaBAMS, MD

 

Dr.Varsha is an Ayurveda doctor with 3 years of experience. She has a degree in the Indian system of medicine and MD in the field of Ayurveda Pharmacology (Dravyaguna). She has diverse work experience as a senior consultant for Government of India health projects in the northeastern and southern parts of India, under CCRAS (Central Council for research in Ayurveda sciences) and as a physician at clinics and rehabilitation centers.

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Ravi Teja TadimallaCo-Editor-in-Chief

 

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